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NOT-NS-18-076 The purpose of this Notice is to inform potential SBIR and STTR applicants about areas of special interest related to the NIH Helping End Addiction Long-term (HEAL) Initiative, an effort to speed scientific solutions to stem the national opioid public health crisis. The National Institute of Neurological Disorders and Stroke (NINDS) is interested in receiving applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NINDS is interested in new screening tools and models focused specifically on pain and development of pain therapies. The National Institute on Drug Abuse (NIDA) is specifically interested in receiving applications to develop new approaches for the prevention and treatment of opioid misuse, overdose and addiction that will help people with opioid use disorder (OUD) achieve and maintain a meaningful and sustained recovery.

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